Uncategorized – Page 24 – The Curious Clinicians

Episode 5: How do diuretics lead to metabolic alkalosis?

On this episode of the podcast, the group answered a question that is often addressed with a wave of the hand: How do diuretics lead to metabolic alkalosis? Along the way, we dissected what is meant by contraction alkalosis, introduced a protein that none of us had heard of until exploring this question, and foundContinue reading “Episode 5: How do diuretics lead to metabolic alkalosis?”

Episode 4: Why did Van Gogh paint with so much yellow?

Based on a tweetorial Avi published in June 30, 2019.

Episode 3: Why does TMP/SMX cause an isolated rise in creatinine?

For this episode of the podcast, we discuss something Hannah became interested in after seeing a question about it on Twitter. Here’s a link to Hannah’s explanation on the topic and the original case tweet. GFR basics To understand why TMP/SMX might lead to an increase in creatinine without a fall in renal function, weContinue reading “Episode 3: Why does TMP/SMX cause an isolated rise in creatinine?”

Episode 2: Why is cancer considered a hypercoagulable state?

For this episode we discuss a tweetorial Tony posted on September 4, 2018. Here’s a link to the full thread: A bit of history In addition to the content covered in the tweetorial, we discussed some history. In 1865, Armand Trousseau, a French physician, was one of the first to describe an association between thrombosisContinue reading “Episode 2: Why is cancer considered a hypercoagulable state?”

Episode 1: Why does fingernail clubbing occur in so many different diseases?

For our first episode, we discussed a topic that Avi covered in a tweetorial posted on February 29, 2020. Here’s a link to the full thread: An ancient exam finding Clubbing was first described 2,500 years ago by Hippocrates, making it perhaps the oldest physical finding in medicine. The term “clubbing” was coined in 1862Continue reading “Episode 1: Why does fingernail clubbing occur in so many different diseases?”