Episode 54 – A Lincoln Theory

What conditions affected Abraham Lincoln? There are certain figures in history whose health has fascinated medical historians and engendered a lot of speculation. Vincent Van Gogh’s affinity for the color yellow was discussed in episode 4. Other examples are Ludwig van Beethoven and the cause of his deafness and the uncertainty surrounding the death ofContinue reading “Episode 54 – A Lincoln Theory”

Episode 53 – Very/Qurious Hypoxemia

Why does pulmonary embolism cause hypoxemia? It almost seems unnecessary to ask why an acute pulmonary embolism causes hypoxemia. There’s a clot in the lungs; of course there is going to be an issue with oxygenation. But, as soon as you begin to interrogate the physiology, it becomes quite clear there is a lot moreContinue reading “Episode 53 – Very/Qurious Hypoxemia”

Episode 52 – Way Back Wenckebach

How does Wenckebach happen? Wenckebach is a fascinating cardiac rhythm. It is a form of heart block with progressive, beat-to-beat prolongation of the PR interval. Eventually, after this progressive PR prolongation, one of the P waves fails to conduct. After this non-conducted P wave, the cycle repeats with a return to the original PR intervalContinue reading “Episode 52 – Way Back Wenckebach”

Episode 51 – Replete with Kare

Why do we replete potassium to >4.0? One of the most common orders placed by inpatient doctors is supplemental potassium chloride in the setting of hypokalemia. Although most don’t learn it in the preclinical years, once a student has spent more than a few hours on the wards they realize nearly everyone repletes the serumContinue reading “Episode 51 – Replete with Kare”

Episode 50 – Antibiotics on the brain

Why can cefepime cause neurotoxicity? Cefepime neurotoxicity is an under-recognized clinical entity and the potential for its presence can confound the assessment of encephalopathic patients. But at the same time, it’s a very effective broad-spectrum antibiotic (i.e., it treats both gram-positive and gram-negative organisms) that clinicians should not fear to use. As background, cefepime isContinue reading “Episode 50 – Antibiotics on the brain”