Avi recently had an interactive feature published in The New York Times Magazine! He examined the discovery of the interstitium and its apparent role as a third circulatory system in the human body. The feature, which had stunning visuals designed by Jérôme Berthier, also explored apparent resonance with the anatomy of acupuncture, as well asContinue reading “Episode 126 – A Third Circulatory System”
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Episode 125 – Why Comics?
On this episode, we were so lucky to be joined by Dr. Grace Farris, who is a hospitalist and the author of a hilarious, poignant, profound graphic memoir of her career in medicine called See One, Do One, Teach One: The Art of Becoming a Doctor. In our conversation with Grace, we explore how sheContinue reading “Episode 125 – Why Comics?”
Episode 124- One of the Fastest Reactions in the Human Body
Why don’t interstitial lung disease patients typically get increased pCO₂? Early on in medical training, you learn to separate a patient’s oxygen from their carbon dioxide. A COPD patient can be heard wheezing from across the ward with a pCO₂ of 80mmHg and actually have a stable O₂ saturation, while their neighbor with interstitial lungContinue reading “Episode 124- One of the Fastest Reactions in the Human Body”
Episode 123 – Why-roid
Why does an autoimmune antibody stimulate the thyroid in Graves’ disease? When we think of antibodies, such as monoclonal antibodies that target specific diseases, we often think of them as blocking receptor-ligand interactions or binding to pathogens to neutralize them. Yet in Graves’ disease, we actually find the opposite of what we would normally expect:Continue reading “Episode 123 – Why-roid”
Episode 122 – When CRP goes missing
Why do patients with active lupus have a low CRP? Although the erythrocyte sedimentation rate (ESR) is typically high in active lupus, C-reactive protein (CRP) is often normal. What’s particularly cool about this finding is that it lends insights into the mechanism of lupus and potentially its cause. The earliest report alluding to this discordanceContinue reading “Episode 122 – When CRP goes missing”
The Curious Clinicians 